Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression.

AUTORES: Troyano-Suárez N, del Nogal-Avila M, Mora I, Sosa P, López-Ongil S, Rodriguez-Puyol D, Olmos G, Ruíz-Torres MP. Oxid Med Cell Longev. 2015;2015:416738. doi: 10.1155/2015/416738. Epub 2015 Oct 25. LINK:

Renal integrin-linked kinase depletion induces kidney cGMP axis upregulation: Consequences on basal and acutely damaged renal function.

Autores: Cano-Peñalver JL, Griera M, García-Jerez A, Hatem-Vaquero M, Ruiz-Torres MP, Rodríguez-Puyol D, De Frutos S, Rodríguez-Puyol M. Mol Med. 2015 Oct 10. doi: 10.2119/molmed.2015.00059. [Epub ahead of print] LINK:

Effect of uraemia on endothelial cell damage is mediated by the integrin linked kinase pathway.

Autores: García-Jérez A, Luengo A, Carracedo J, Ramírez-Chamond R, Rodriguez-Puyol D, Rodriguez-Puyol M, Calleros L. J Physiol. 2015 Feb 1;593(3):601-18; discussion 618. doi: 10.1113/jphysiol.2014.283887. Epub 2014 Dec 18. Link →;jsessionid=758D897C821ADAD49D573E93B56EC871.f04t04 Abstract

The active form of vitamin D, calcitriol, induces a complex dual upregulation of endothelin and nitric oxide in cultured endothelial cells.

Autores: Martínez-Miguel P, Valdivielso JM, Medrano-Andrés D, Román-García P, Cano-Peñalver JL, Rodríguez-Puyol M, Rodríguez-Puyol D, López-OngilS Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1085-96. doi: 10.1152/ajpendo.00156.2014. Link →   Abstract Despite

Hyperosmolarity induced by high glucose promotes senescence in human glomerular mesangial cells.

Autores: del Nogal M, Troyano N, Calleros L, Griera M, Rodriguez-Puyol M, Rodriguez-Puyol D, Ruiz-Torres MP. Int J Biochem Cell Biol. 2014 Sep;54:98-110. doi: 10.1016/j.biocel.2014.07.006. Link → Abstract Hyperglycemia is involved

Relevant role of PKG in the progression of fibrosis induced by TNF-like weak inducer of apoptosis

Autores: Martín P, Mora I, Cortes MA, Calleros L, García-Jerez A, Ortiz A, Rodríguez-Puyol M, Rodríguez-Puyol D, Olmos G. Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F75-85. doi: 10.1152/ajprenal.00398.2013 Link →

Impact of implementing ISO 9001:2008 standard on the Spanish Renal Research Network biobank sample transfer process.

Autores: Cortés MA, Irrazábal E, García-Jerez A, Bohórquez-Magro L, Luengo A, Ortiz-Arduán A, Calleros L, Rodríguez-Puyol M. Nefrologia. 2014 Sep 26;34(5):552-60. doi: 10.3265/Nefrologia.pre2014.Apr.12292. Link → Resumen Antecedentes: La certificación de biobancos